In response to the heightened oxidative stress associated with malignant transformation, cancer cells activate a comprehensive antioxidant defense pathway that, paradoxically, shields them from ferroptotic cell death (4)
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Liver disease may affect glutathione metabolism, and certain autoimmune conditions may be influenced by supplementation
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Do not exceed the dose recommended by your physician, as it can result in nausea, diarrhoea, or cramps
The fourth step of the mechanism consists of a second Tyr9 rearrangement that allows direct interaction of the Tyr9 phenolate with the glutathione thiol