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3, 2022, pp
To view or add a comment, sign in Next-Generation GLP-1Based Therapies for Obesity: Comparative Weight Loss Outcomes Mean Percentage Weight Loss in Phase 3 Trials Orforglipron (oral GLP-1 receptor agonist) 6 mg: 7.5% 36 mg: 11.0% Placebo: 2.0% n 3,100
The SELECT trial (N=17,604) later showed that semaglutide 2.4 mg reduced major adverse cardiovascular events by 20% in adults with overweight or obesity and established cardiovascular disease, even without diabetes [17]
Compounded injectable GLP-1s typically come in multi-dose vials requiring the patient to draw and measure their own dose with a syringe
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