tirzepatide side effects long term caused roughly half as many patients to stop treatment because of gastrointestinal as semaglutide. In the first major head-to-head obesity trial, GI side effects caused treatment discontinuation in: Tirzepatide bloating on tirzepatide Zepbound (Tirzepatide)

Others struggle with stress eating or shift-work schedules

There is currently no cure for nAMD and it is a condition that can potentially cause blindness

2019 Sep 13;11(9)

GLP-1 is a naturally occurring gut hormone that signals fullness to the brain, slows gastric emptying, and helps regulate insulin and blood sugar

Use Without Supervision In June 2024, COFEPRIS warned about the risks of using semaglutide and liraglutide without medical supervision

PCAC member Elizabeth Rebello, a professor in the Department of Anesthesiology and Perioperative Medicine at the University of Texas MD Anderson Cancer Center, cited the "lack of efficacy data and randomized controlled trials" as her basis for her no vote