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Heme and iron metabolism Another critical function of the NRF2 antioxidant program is the regulation of iron metabolism

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doi: 10.1016/j.tins.2019.04.004 59 HatashitaY.WuZ.FujitaH.KumamotoT.LivetJ.LiY.et al

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Similarly, rbohF and rbohD/F mutants infected by TuMV had increased activity of GST and GR, strongly downregulated GPXL, and highly reduced levels of lipid peroxidation

A recent narrative review found that while it can be effective, results are inconsistent and often require ongoing maintenance (PMC narrative review)