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Aged mice were divided into control and treatment groups, with the latter receiving intraperitoneal injections of FOXO4-DRI at doses of 0.5 mg/mL and 5 mg/kg every other day for 30 days, while controls received PBS

Conflict of interest statement The authors declare that they have no conflict of interest.

This product is a nutritional supplement and should not be used as a substitute for a varied and balanced diet or a healthy lifestyle

These results further support that axonal fusion requires a moderate level of ferroptosis signaling and is inhibited by a high level