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Permeability studies After checking the cell monolayer integrity, the monolayers were transferred to new plates

Backbone modifications include fatty-acid acylation that supports albumin binding and extends plasma half-life to approximately six days, which underpins the once-weekly subcutaneous dosing pattern used across the published clinical trials

a , representative Sma stained liver sections, quantification is provided in Fig

10.1146/annurev-nutr-071816-064732 Ann Rev Nutr

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