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Other brain benefits The GLP-1 agonists reduce central nervous system inflammation and stimulate brain growth factor proteins, suggesting neuroprotective benefits, but does that lead to benefits for neuropsychiatric disorders

Researchers at the University of Virginia, supported by National Institutes of Health funding, found that oral small-molecule GLP-1 receptor agonists, including orforglipron, penetrate deeper into the brain than previously understood

Most injection-site bruises fade within 710 days and are typically mild

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We found that activation of NTSVTA circuits suppressed cocaine seeking in rats without affecting ad libitum food and water intake