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Considering that OPG and RANKL are mainly secreted by osteoblasts to regulate bone metabolism, the inhibition of MOTS-c-induced osteoclastogenesis may be caused by an increase in the OPG/RANKL ratio

"Your durability will also go down, so your ability to do longer stages, particularly back-to-back days of riding, is going to be impaired as well." Cycling is already known to negatively impact bone density, and with the addition of GLP-1s, the risk becomes greater

A study published in 2023 compared the keto diet and a more general low carb diet in mice by sex

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Timing matters more with this tablet than with the weekly injection

This gives you a starting point so you can actually measure how much a future treatment helps