is glp 1 bad for kidneys Role of GLP-1 Agonists & SGLT-2 Inhibitors in Kidney Care Potential kidney-protective and other effects

With the matched group on semaglutide, 28 reported gastroparesis.[ref][ref] Diabetic retinopathy: Two clinical trials in people with diabetes linked GLP-1 RA drugs to an increased risk of diabetic retinopathy, while other studies show that the drugs were not associated with the eye disease

Guan X, Dwivedi C, Kim SY, Fine T, Ratzsch A, Seefeldt T, et al

GLP-1 receptor agonists enhance glucose-dependent insulin secretion from pancreatic beta cells, suppress inappropriate glucagon release, slow gastric emptying, and promote satiety through central nervous system pathways

This can lead to inflammation and a variety of health issues ranging from high blood pressure and diabetes to Alzheimers disease and more

For PCA analysis, all metabolites were used following quantile-normalization in the Statistical Analysis module of MetaboAnalyst 6.0

Serious but Rare Side Effects: Increased heart rate, mood changes, kidney stones, and birth defects if used during pregnancy