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[11] It has the amino acid sequence Ac-Nle- cyclo [Asp-His-D-Phe-Arg-Trp-Lys]-OH, [16] and is also known as cyclo -Ac-[Nle 4 ,Asp 5 ,D-Phe 7 ,Lys 10 ]-MSH-(4-10) (a substitutional name)

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Gastrointestinal effects are among the most frequently reported adverse events with GLP-1 therapies and typically include nausea, vomiting, diarrhea, constipation, and abdominal pain

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The MFI was determined by flow cytometry (LSRFortessa TM