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You stay on the treatment for months to a year until you achieve your desired results

Serious side effects Common (may affect up to 1 in 10 people) complications of diabetic eye disease (retinopathy)

S1 Flow diagram of included studies

Based on our market checks, it is our sense that GLP-1s had some impact on bariatric surgery volumes in the second quarter

During this phase, you can expect: Clear instructions on how your injections are administered Guidance on proper injection technique if self-administering at home Consistent weekly dosing to support steady weight loss Appetite reduction and improved portion control Support from our medical team if you have any questions or concerns 4

Figure 2c: From step 1 (left) to steps 2 and 3 (right)