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dosing with 100 nmol kg 1 MK-801, 100 nmol kg 1 GLP-1, 100 nmol kg 1 GLP-1MK-801 or vehicle

Instead, each serves a different purpose depending on the biological questions being investigated

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In physiological systems, GLP-1 is released from intestinal L-cells following nutrient intake and contributes to insulin signaling, appetite regulation, and gastric emptying modulation

By stimulating two hormone pathways, it enhances insulin secretion, more effectively suppresses appetite, and supports a greater reduction in blood sugar levels