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Look for: Texture changes: Thickened, rubbery, or spongy areas indicate early lipohypertrophy

Start your intake How Tirzepatide Influences Hormonal Balance and Your Cycle Tirzepatide works by mimicking glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP), two hormones that regulate appetite, blood sugar, and energy expenditure

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These include: Lifestyle interventions (dietary advice, physical activity programmes) Licensed pharmacotherapy such as orlistat, or GLP-1 receptor agonists including semaglutide 2.4 mg (Wegovy, NICE TA875) or tirzepatide (Zepbound) where clinically indicated and available Referral to tier 3 or tier 4 weight management services , including bariatric surgery assessment where appropriate Information on NHS weight management services and eligibility for licensed treatments is available via the NHS website and NICE guidance

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Kang YJ, Diep YN, Tran M, Cho H (2020) Therapeutic targeting strategies for early- to late-staged Alzheimers disease