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7d), confirming that the need to increase mitochondrial mass in 5FU-treated cells is driven by a dependence on increased mitochondrial activity, and metformin can block this mitochondrial adaptation to prevent drug tolerance in tumours
The FDA early this year removed that black box warning after a comprehensive analysis of many thousands of patients who have taken this medication, and across that huge cohort, there has been no increased risk of depression or suicidality. What further research still needs to be done about GLP-1 medications and alcohol use
In the meantime, artificial sweeteners and processed meats should be avoided
GCGR = glucagon receptor (energy burn and fat oxidation)
This process can be accelerated due to poorly managed stress or distress, malnutrition, poor diet, environmental toxins, etc
Herpes simplex virus type 1 modifies the protein composition of extracellular vesicles to promote neurite outgrowth and neuroinfection
