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A 2022 study found patients regained approximately two-thirds of lost weight within one year of stopping (Wilding et al., Diabetes Obesity and Metabolism 2022)
References Gasoyan H, Butsch WS, Schulte R, et al
A clinical study of a GLP-1 RA highlighted that participants who followed dietary advice and injected weekly saw an average 18% lower energy intake compared to placebo, with significant reductions in body weight and cardio-metabolic risk
Saline can cause precipitation of the peptide
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