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Hyperinsulinemia and insulin resistance promote tumor growth through various mechanisms: directly by activating the insulin receptor signaling pathway and indirectly by stimulating the insulin-like growth factor (IGF) receptor system, which in turn fosters cellular proliferation, migration, and invasion while inhibiting programmed cell death [11]

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By activating GLP-1 receptors in appetite-regulating brain regions and slowing gastric emptying, the medication creates earlier satiety and prolonged fullness after meals

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M., Buse, J

Makes me feel great while losing weight and giving me my confidence