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Doses Per Vial 5mg vial: At 2.5mg/week = 2 weeks At 5mg/week = 1 week 10mg vial: At 2.5mg/week = 4 weeks At 5mg/week = 2 weeks At 7.5mg/week = 1.3 weeks At 10mg/week = 1 week 15mg vial: At 2.5mg/week = 6 weeks At 5mg/week = 3 weeks At 10mg/week = 1.5 weeks At 15mg/week = 1 week A 10mg vial covers the first month of a standard escalation at 2.5mg/week

Additionally, tirzepatide administration over an extended period raised BAT levels of several amino acids that have been demonstrated to be elevated in response to cold exposure

Target: 4.5 mg weekly by Weeks 78

10.1038/nature07540 Nature

As someone who has spent years in drug development and scaleup, I see in them both the appeal of a clever receptor agonist and the red flags of a product that has largely escaped the discipline of proper clinical development and quality control

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