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People taking semaglutide also may eat less salt because the drug curbs cravings for salty, high-fat snacks and foods

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Using an appropriate skin cleanser and moisturizer is very important in general, he says

The study did, however, also highlighted several negative side effects, including constipation (118 occurrences), diarrhea (100 events), and abdominal pain (41 events per 1,000) ( Abdominal pain, nausea, vomiting, and diarrhea are among the gastrointestinal adverse effects linked to GLP-1 RAs

Launched by Novo Nordisk in 2026, semaglutide in its oral form became the first GLP-1 drug intended specifically for weight loss, contrasting with Rybelsus, which is used primarily for type 2 diabetes

Prior serious hypersensitivity to a GLP-1 medication