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GIP slows gastric motility, enhances insulin release from the pancreas, and contributes to satiety signaling in ways that are additive to GLP-1 effects
GLP-1 drugs can be helpful while you are taking them, but gastric sleeve changes the trajectory of your weight and metabolism in a much more lasting way
doi:10.1056/NEJMoa1504720 49
Mean body weight decreased from 98.64 23.28 kg at baseline to 86.02 19.47 kg at follow-up, corresponding to a mean reduction of 12.63 24.03 kg
Importantly, no serious AEs were observed, and only one patient (0.8% of the safety cohort) discontinued treatment owing to mild injection site pain
This constant but weaker bile flow can sometimes make it harder for your body to break down and absorb fats efficiently
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