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This work further highlights how physiologically relevant in vitro systems are becoming a mechanistic backbone for predicting oral bioavailability, improving translational relevance, and supporting the development of next-generation therapeutics
"Repetitive Transcranial Magnetic Stimulation in Chronic Pain: A Review of the Literature." Archives of Physical Medicine and Rehabilitation , 100(8), 1547-1559
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Corticosteroids Corticosteroids provide rapid symptom relief but carry substantial risks: immunosuppression, impaired wound healing, tendon weakening with increased rupture risk, hyperglycemia, and osteoporosis with chronic use
Treatment with GLP-1 and exendin-4 significantly increased neurite length in cultured DRG neurons, potentially accounting for the increased nerve fibers observed in IBS biopsies [55] (Fig
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