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Individuals trying to conceive or taking isotretinoin should avoid Vitamin A
Jordan, S
Yoo M-H, Gu X, Xu X-M, Kim JY, Carlson BA, Patterson AD et al
Tretinoin can cause temporary dryness, flaking, or purging during the adjustment period (niacinamide often helps minimize this)
its formulated with a combination of vitamins, minerals, antioxidants, and plant-based ingredients that support skin repair, reduce the effects of aging, and enhance a natural glow
In humans theres essentially no data on half-life, mechanism, or long-term side effects (source)
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