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Schrag D, Uno H, Rosovsky R, et al

In injured tissue, improved blood supply may help deliver oxygen, nutrients, immune cells, and repair signals to the healing area

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Research efforts expanded throughout the 1990s and 2000s as investigators explored the peptide's potential influence on tissue repair, angiogenesis, and gastrointestinal integrity

Clinically, however, the evidence is mixed : Vitamin B12 has a well-established role in energy metabolism, especially in deficient individuals

J Bacteriol 182:67426750 Galhardo RS, Rocha RP, Marques MV, Menck CFM (2005) An SOS-regulated operon involved in damage inducible mutagenesis in Caulobacter crescentus