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Semaglutide also outperformed placebo in the secondary dual endpoint of MASH resolution with one-stage fibrosis improvement (32.8% vs
Body composition scans are repeated to confirm that weight loss is coming from fat rather than lean tissue
The dose is then increased to 7 mg daily
Quick Answer: Semaglutide does cause some muscle loss, with approximately 2540% of total weight lost coming from lean body mass, similar to other weight loss methods
If side effects are severe or persistent, patients should consult their prescriber about potential dose adjustments
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