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In light of current findings, it should be noted that LC combined with leucine or leucine alone supplementation does not improve the effectiveness of RET in healthy aged women, at least in studied doses

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Retatrutide is being studied in ongoing clinical trials, including programs evaluating obesity, overweight with weight-related conditions, type 2 diabetes, obstructive sleep apnea, osteoarthritis, chronic low back pain, cardiovascular and renal outcomes, and metabolic dysfunction-associated steatotic liver disease