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These metabolites also help to maintain epithelial and endothelial barrier integrity, which reduces systemic inflammation and the spread of microglial priming

Regional differences in nutrient-induced secretion of gut serotonin

doi: 10.1002/imt2.88 372 ZhangB.YangH.CaiG.NieQ.SunY

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Clinical trial data shows diarrhea rates of 19-23% across doses, with nausea remaining the predominant side effect at 24-31%

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