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Its interactions with the vagus nerve have been investigated in the context of brain-gut axis effects, including gastroparesis (delayed gastric emptying), where BPC-157 has shown consistent pro-motility effects in preclinical models through vagal cholinergic pathways

Necroptosis and the upregulation of Drp1 and RB were alleviated by the DNM1L silencing using a siRNA or pharmacological inhibition of Drp1