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Besides, the encapsulated proteins/peptides are susceptible to harsh processing conditions associated with microsphere fabrication methods, including exposure to organic solvent, shear stress, and temperature fluctuations

Firstly, it is not routinely tested, and secondly, low levels are often labeled as normal e.g

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Different techniques are used to ensure quality control of finalized preparation like HPLC (high performance liquid chromatography) or gas chromatography, spectrophotometry, UV detection, measurement of osmolality & pH etc