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A 2,700person realworld study presented at the 2025 European Congress on Obesity showed an average 16% weightloss over 64 weeks at microdose levels of semaglutide

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Transdermal semaglutide administration in mice: Reduces body weight by suppressing appetite and enhancing metabolic rate

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Pregnant or breastfeeding women should not use semaglutide, as its safety in these populations has not been fully established