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After an initial consultation, the dosage and treatment plan are customized based on skin condition and health history
The binding of T3 to TRs induces a conformational change in the receptor, which allows the receptor to bind to thyroid hormone response elements (TREs, specific DNA sequences) in the promoter regions of target genes (Simons 2003)
DOI: 10.1210/en.2005-1089 87
Wang Y, Branicky R, No A, Hekimi S
Whether this pathway plays an important role under pathological conditions is unknown, as CD163 has not been shown to uptake the dimer form of Hb, which is more relevant in SCD (Andersen et al., 2012)
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