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A 2011 study of more than 3000 participants in the Cooperative Health Research in the Augsburg Region (KORA) cohort found sex differences for up to 78% of metabolites, including PCs (Mittelstrass et al

On the other hand, it is still not entirely clear whether the hepatic effects of GLP-1 are direct or indirect, as recent studies have not clearly demonstrated the presence of GLP-1 receptors in human hepatocytes

10.1056/NEJMoa043160 38 RamaekersV

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