Long-term genotoxicity and carcinogenicity are not established in humans
And as indicated by the list above of upcoming trials, there may be several new indications in the near future
And so in this case they just chose to agonize it, but theres one coming out where they antagonize it
Although traditional antidepressants, such as selective serotonin reuptake inhibitors (SSRIs) and monoamine oxidase inhibitors (MAOIs), can alleviate depressive symptoms to some extent, they have limitations in efficacy and are associated with significant side effects
The evaluation of the long-term effect of the therapy with IBAT inhibitors on the progression towards fibrosis, cirrhosis of the liver, and oncological risk must be carefully investigated
& Los agonistas de receptor de GLP-1 han mostrado efectos beneficiosos en modelos preclnicos de enfermedades neurodegenerativas, aunque el establecimiento de su eficacia clnica en la prevencin y tratamiento requiere estudios adicionales
