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Fecal impaction occurs when a mass of dry, hard stool becomes lodged in the rectum, usually in individuals who have been constipated for an extended period of time (UMMC 2015a)

The decline in Bacteroidetes impairs intestinal barrier function and exacerbates systemic inflammation, while the reduction in Firmicutes leads to an accumulation of TMAO precursors, which promote cardiac injury

GLP-1 plays a crucial role in regulating blood sugar levels and appetite

CNS GLP-1 regulation of peripheral glucose homeostasis

Mou S, Zhou M, Li Y, Wang J, Yuan Q, Xiao P, et al

TRICARE covers Mounjaro (same active ingredient as Zepboundtirzepatide) for Type 2 diabetes with prior authorization