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Registration clinical trials show that 16-37% of patients discontinue within a year (109111)

Selective serotonin reuptake inhibitors (SSRIs) : Antidepressants such as fluoxetine or sertraline may help reduce binge frequency, particularly when depression or anxiety co-exists, though they are used off-licence for this indication

Obesity and Metabolism, 12(1), 16-19

Professor Adam Balen from the Royal College of Obstetricians and Gynaecologists emphasizes: "A clinician may consider prescribing this medicine 'off-label' if they think it would benefit a patient with PCOS, but this would need a careful discussion with them about the benefits and potential risks." Beyond the physical benefits, these treatments are reshaping how patients view their condition

Moreover, we understand that people have busy schedules that may not allow them to visit our office on a weekly basis

However: Follow-up durations were typically 68 weeks