Srinivasan, U., Mieyal, P
2.3 Ferroptosis and other cell death pathways Ferroptosis differs from other cell death modalities in both molecular mechanisms and morphological characteristics, since it is a unique iron-dependent type of controlled cell death triggered by LP and GPX4 inactivation (Table 1)
These pathways are implicated in amino acid turnover, redox balance, neurotransmitter regulation, and mitochondrial function, suggesting coordinated metabolic perturbations in ASD
Lipoic acid also protected liver from oxidative stress-induced liver injury in methotrexate-treated rats through the activation of Nrf-2 pathway and other anti-inflammatory pathways (37)
1f), long-term HFD consumption significantly increased hepatic protein S -glutathionylation when compared with a control diet, as demonstrated by marked elevations in hepatic protein-SSG adducts by western blot analysis
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