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It consists of replacing four consecutive amino acid residues in the sequence of an -helical peptide by an -helicomimetic oligourea segment of three residues to generate the analogous peptideoligourea hybrid

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Similarly, Vitamin B12 is also essential in the metabolism of fatty acids and proteins

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This makes it unique among cognitive compounds: it can be taken in forms that reach the brain directly, where it interacts with specific receptor systems that drive the physical growth of neural connections