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Fras et al., 2016)

Furthermore, FMO3 has been shown to serve as a central regulator of tissue cholesterol balance and to be involved in insulin resistance and dyslipidemic changes in mouse models, suggesting the FMO3 and TMAO pathway as potential mediators of diabetes associated atherosclerosis 52,53

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In another study, semaglutide positively affected the cognitive and molecular symptoms of AD and restored oxytocin levels in APP/PS1 mice and in human brain organoid models [52]

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