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A recent metanalysis [87] has assessed the impact of oral antidiabetic drugs (OADs) and GLP-1 receptor agonists on left ventricular diastolic function in patients with type 2 diabetes, the findings indicated that, compared to placebo and OADs, only liraglutide significantly improved left ventricular diastolic function

While the powder gets good reviews on taste, some reviewers note the lack of flavor options as a downside

T1R3 knockout mice exhibit impaired GLP-1 secretion and glucose intolerance (130)

If a higher maintenance dose is not tolerated, reduction to a lower dose is indicated and may lead to an optimal treatment response

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It may also promote cellular health by helping prevent the accumulation of long-chain fatty acids in cells