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Notably, Zhang et al

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Treatment with Fer-1 effectively inhibited ferroptosis and significantly alleviated fibrotic changes in these cells

In addition, GLP-1R stimulation activates insulin signaling pathways and regulates gene expression, decreasing systemic insulin resistance and brain insulin resistance in patients with AD (Dahiya et al., 2025)

This rapid breakdown severely limits its therapeutic potential in native form

Prevention and Management of Chemotherapy-Induced Peripheral Neuropathy in Survivors of Adult Cancers: ASCO Guideline Update