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Conversely, if a patient presents with pernicious anemia or severe neurological signssuch as intense tingling in the hands, memory loss, or muscle weaknessthe dosage remains the same (usually 1,000 mcg), but the frequency increases significantly
The MR analysis relies on three key assumptions: (1) the genetic variants must be associated with the exposure, (2) the genetic variants must influence the outcome through the exposure, and (3) the genetic variants must be independent of all confounding factors
pp 241266 Castejn M, Plaza A, Martinez-Romero J et al (2020) Energy restriction and colorectal cancer: a call for additional research
This is why many people find success by combining different support tools
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