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Statins inhibit coenzyme Q10 synthesis, which can impair electron transport chain function and increase mitochondrial oxidative stress in skeletal muscle, leading to statin-associated myopathy
Depression is not commonly associated with semaglutide use, but changes in mood can occur with any medication that affects hormones or appetite
However, there was no significant difference in adverse CVEs or all-cause mortality when compared with those taking SGLT2 inhibitors
One last thing, your cleanser
Your doctor should assess several factors before approving discontinuation, including your current weight status and trajectory, the presence and control of obesity-related comorbidities (type 2 diabetes, hypertension, sleep apnea, cardiovascular disease), your readiness and capacity to implement intensive lifestyle modifications, available support systems and resources, and your history of weight cycling or previous weight loss attempts
