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Regulatory status further limits clinical use, since BPC-157 is not approved for medical treatment and available data remains largely experimental

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This strategy is particularly promising when used in combination with immune checkpoint inhibitors, such as anti-PD-1/PD-L1 antibodies, which have shown success in some cancers but have inconsistent effectiveness in solid tumors because of the TMEs strong immunosuppressive properties [159]

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Sikiric et al., 2020b), to induce a simultaneous healing, even in different tissues (and therefore the healing of diverse fistulas (Klicek et al., 2008