It can be fatigue, lack of mental focus, brain fog, muscle fatigue, and aches and pains
(1) modulating antigen presentation to lymphocytes, thereby influencing cytokine production and type of response (cellular or humoral) that develops, (2) enhancing proliferation of lymphocytes, thereby increasing magnitude of response, (3) enhancing killing activity of cytotoxic T cells and NK cells, and (4) regulating apoptosis, thereby maintaining control of the immune response
10.1038/s41467-018-07113-0 217 ThakkarJ
Metabolic studies Animals were given either 6 g/kg glucose or distilled water (2 mL/100 g body weight, n = 10 for all groups) by gavage every 6 h (at 06:20, 12:20, 18:20, and 24:20 h) for 38 days, defined as the long-term oscillating glucose (LOsG) or sham group
10.1126/science.aao5774 514 ZhaoY.CongL.JaberV.LukiwW
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