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Transient breathing discomfort or mild bronchospasm reported in some individuals, particularly those with asthma or sensitive airways
We report a technique inspired by the HaloTag technology, which employs nucleophilic substitution at chloroalkane-functionalised ligands by a specific aspartate residue
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In db/db mice and HG-treated TECs, ectonucleoside triphosphate diphosphohydrolase 5 overexpression inhibited apoptosis to preserve TECs via regulating the protein N-glycosylation rate in ER (83)
These findings not only advance our understanding of the molecular mechanisms controlling pluripotent state transitions but also suggest potential therapeutic strategies for manipulating cell fate in regenerative medicine applications
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