In addition, genes involved in fatty acid oxidation (e.g., hydroxyacyl-CoA dehydrogenase trifunctional multienzyme complex subunit beta [HADHB], CPT1, and CPT2), as well as genes involved in fatty acid synthesis (e.g., acetyl-CoA carboxylase alpha [ACACA] and fatty acid synthase [FASN]) were upregulated (194)
It is not a free pass continuous, non-pulsatile overstimulation is the theoretical concern behind why the short-acting, pulse-mimicking forms are generally preferred but the it will shut me down like a steroid worry is not how this class of compound works
The overall result is a progressive deficiency that worsens as the condition develops
Some CKD patients will need to monitor their potassium levels closely and adjust their intake of high-potassium foods, such as oranges, bananas, avocados, potatoes, tomatoes, beans, lentils, nuts, and some whole grains, as well as many herbal medicines and salt substitutes
Vacante, L
PMC 1171394