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Thyroid tumors Liraglutide has been associated with an increased risk of thyroid C-cell tumors in animal studies, although the relevance of this finding to humans is uncertain
Clearly, obesity is a huge health problem that carries all kinds of horrible risks
Patients with renal impairment can generally use semaglutide and tirzepatide without dose adjustment, though monitoring for dehydration from gastrointestinal side effects is important
Moreover, while direct comparisons cannot be made without head-to-head trials, some outcomes in diabetes CVOTs have been within the range expected for cardiorenal therapies such as statins, aspirin and antihypertensives [116], despite being added on top of a standard of care that often included these therapies (Fig