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1:2500, Abcam, Cambridge, UK), Drp-1 (1:2000, Novus Biotechnology, Littleton, CO, USA), Opa-1 (1:2000, Novus Biotechnology, Littleton, CO, USA), LC3A/B (1:2000, Cell Signaling Technology, Danvers, MA, USA), Tom-20 (1:2000, Santa Cruz Biotechnology, Dallas, TX, USA) and MnSOD (1:2000, Millipore, Billerica, MA, USA), Pink-1 (1:1000, BioVision Incorporated, Milpitas, CA, USA), Fis-1 (1:500, Santa Cruz Biotechnology, Dallas, TX, USA) and Parkin (1:500, Cell Signaling Technology, Danvers, MA, USA) for overnight
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Um, do you have any other thoughts on this that we didnt get to in this episode
3 If A1C goals are not achieved after 3 months of dual therapy, triple therapy is subsequently recommended
Previous scRNA-seq studies of LPC and CPZ models have described distinct disease-associated oligodendrocyte (DAO) states, including similar transcriptional changes to those in Alzheimers disease models, but have not directly compared LPC and CPZ 8,9,10
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