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If youve been treated for hypothyroidism and still feel symptomatic despite normal TSH, a full thyroid panel and a conversation with an endocrinologist is worth pursuing before or alongside GLP-1 treatment

The long-term effects of this are not known

Although lowering of insulin levels with diet or drugs such as metformin and diazoxide seems generally beneficial, some practitioners also utilize strategic elevations of insulin levels in combination with chemotherapeutic drugs

Shaman AM, Bain SC, Bakris GL, et al

Insulin transport across the bloodbrain barrier can occur independently of the insulin receptor

Haemmerle G., Lass A., Zimmermann R., et al