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Future directions Available research on AOX therapy is surrounded by several limitations and biases, including small sample sizes, heterogenous patient populations and inclusion criteria, poor study designs, and inconsistent reporting of clinical outcomes
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Dermatological reactions represent the most consistently documented side effect of excessive B12 intake
doi: 10.1016/j.bbr.2020.112919
Appetite and Ghrelin Pathway Effects Because GHS-R1a is the same receptor activated by endogenous ghrelin, the body's primary hunger-signaling hormone, GHRP-6 stimulates appetite through identical hypothalamic pathways
The most common side effects are mild and include transient skin flushing or warmth during infusion
