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& Vogel, V
ALA can occasionally cause heartburn or nausea and may affect blood sugar in some people
The disconnect between short plasma half-life and prolonged therapeutic effects observed in many studies supports tissue-level mechanisms extending beyond circulating peptide concentrations
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doi: 10.1016/j.phrs.2022.106563 71 CoutinhoLLJuniorTCTRangelMC
Since 90% of the bodys serotonin originates in the gut, these peripheral effects could influence central serotonergic tone through vagal signaling
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