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Naiki-Ito A, Asamoto M, Hokaiwado N, Takahashi S, Yamashita H, Tsuda H, Ogawa K, Shirai T

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The in-source parameters were: gas temperature 150 C, gas flow 11 l min 1 , nebulizer pressure 40 psi, sheath gas temperature 300 C, sheath gas flow 11 l min 1 , capillary voltage 2,000 V, and nozzle voltage 2,000 V

Patients gradually increase the dosage to the 2.4-milligram maintenance dose